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Difference Between Cocaine vs Amphetamine

  • Post last modified:March 16, 2023
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Definition of Cocaine

Cocaine is a highly addictive stimulant drug made from the leaves of the coca plant native to South America. It is a white powder that is typically snorted or dissolved in water and injected. Cocaine can also be made into a rock crystal form, which is known as crack cocaine. It is a Schedule II controlled substance in the United States and is illegal to possess, use, or distribute. It produces intense feelings of euphoria and energy, but can also lead to serious health problems, including heart attack, stroke, and seizures. Long-term use can also lead to addiction, depression, and other mental health problems.

Definition of Amphetamine

Amphetamine is a stimulant drug that belongs to the phenethylamine class of compounds. It is a white, odorless powder that can be taken orally, inhaled, or injected. It is used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, a sleep disorder. It increases the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine, which can improve attention and focus, but also increase heart rate, blood pressure, and body temperature. It is a Schedule II controlled substance in the United States and is illegal to possess, use, or distribute without a prescription. Long-term use can lead to addiction, as well as physical and mental health problems such as anxiety, insomnia, and cardiovascular issues.

Cocaine VS Amphetamine – Differences

Cocaine and amphetamine are both stimulant drugs that affect the central nervous system, but they have some key differences.

  1. Chemical structure: Cocaine is a tropane alkaloid and amphetamine is a phenethylamine.
  2. Legal status: Cocaine is a Schedule II controlled substance and is illegal to possess, use, or distribute without a prescription. Amphetamine is also a Schedule II controlled substance, but it is legally available in prescription form.
  3. Medical uses: Cocaine has limited medical uses, primarily as a local anesthetic for certain surgeries. Amphetamine is used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.
  4. Mode of Administration: Cocaine is typically snorted or injected, while amphetamine can be taken orally, inhaled, or injected.
  5. Side Effects: Cocaine use can lead to serious health problems such as heart attack, stroke, and seizures, while amphetamine can lead to anxiety, insomnia, and cardiovascular issues.
  6. Potency: Cocaine is considered more potent than amphetamine in terms of effects and addiction potential.
  7. Duration of effect: The effects of cocaine are shorter-lived than those of amphetamines.
  8. Withdrawal: Amphetamines withdrawals are typically less severe than cocaine withdrawals.

It’s worth noting that both drugs can be highly addictive and can lead to serious health problems with prolonged use. Misuse of these drugs should be avoided and it is always recommended to take it under medical supervision.

Comparison Chart

Here is a comparison chart of some key differences between cocaine and amphetamine:

Cocaine Amphetamine
Chemical structure Tropane alkaloid
Legal status Schedule II controlled substance, illegal without prescription
Medical uses Local anesthetic for certain surgeries
Mode of Administration Snorted or injected
Side Effects Heart attack, stroke, seizures, addiction
Potency More potent
Duration of effect Shorter-lived
Withdrawal Severe

It’s worth noting that this is not an extensive list and other differences may exist. Misuse of these drugs should be avoided and it is always recommended to take it under medical supervision.

Similarities Between Cocaine VS Amphetamine

Cocaine and amphetamine are both stimulant drugs that affect the central nervous system, so they have some similarities:

  1. Mechanism of action: Both drugs increase the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine, which can improve attention and focus.
  2. Psychoactive effects: Both drugs produce intense feelings of euphoria and energy, and can lead to increased sociability and talkativeness.
  3. Addiction potential: Both drugs have a high potential for addiction, and long-term use can lead to physical and psychological dependence.
  4. Health risks: Both drugs can lead to serious health problems with prolonged use, such as cardiovascular issues, anxiety, and depression.
  5. Legal consequences: Both drugs are Schedule II controlled substances in the United States, which means that they are illegal to possess, use, or distribute without a prescription.
  6. Medical supervision: Both drugs are only legal for medical use under the supervision of a licensed healthcare professional.

It’s worth noting that this is not an extensive list and other similarities may exist. Misuse of these drugs should be avoided and it is always recommended to take it under medical supervision.

Frequently Asked Questions

Here are some frequently asked questions about cocaine and amphetamine:

  1. What are the long-term effects of using cocaine or amphetamines?
    Long-term use of both drugs can lead to addiction, as well as physical and mental health problems such as anxiety, insomnia, cardiovascular issues, depression and in some cases it can also lead to psychosis.
  2. How do cocaine and amphetamines differ in terms of addiction potential?
    Both drugs have a high potential for addiction, but cocaine is considered more potent in terms of effects and addiction potential than amphetamines.
  3. Are there any medications that can help with addiction to cocaine or amphetamines?
    Medications such as methadone, buprenorphine, and naltrexone can be used to treat addiction to opioids, but there are no FDA-approved medications specifically for treating addiction to cocaine or amphetamines. Behavioral therapy and support groups can also be effective in treating addiction to these drugs.
  4. Can you overdose on cocaine or amphetamines?
    Yes, it is possible to overdose on both drugs. Symptoms of a cocaine overdose include seizures, heart attack, stroke, and coma, while symptoms of an amphetamine overdose can include high fever, hallucinations, seizures, and heart failure.
  5. Can you mix Cocaine and Amphetamines?
    Mixing Cocaine and Amphetamines is not recommended as it increases the risk of overdose and other serious health problems. It is also illegal.
  6. Are there any legal alternatives to Cocaine or Amphetamines?
    There are no legal alternatives to these drugs. It is always recommended to consult a doctor or a healthcare professional for any medical condition or to treat any disorder. Misuse of drugs should be avoided.

Reference Books

There are many books available that provide detailed information on cocaine and amphetamines. Here are a few reference books that may be of interest:

  1. “Cocaine: From Medical Marvel to Modern Menace in the United States” by Joseph Spillane – This book provides a historical perspective on the use of cocaine and its impact on society.
  2. “The Amphetamines: Toxicity and Addiction” by George U. Rose – This book provides a comprehensive overview of the pharmacology, toxicology, and addiction potential of amphetamines.
  3. “Pharmacology of Cocaine” by Richard D.T. King – This book provides a detailed understanding of the pharmacology of cocaine, including its mechanism of action and toxicology.
  4. “Amphetamines and Other Stimulants” by Barbara Krantz – This book provides a comprehensive overview of the history, pharmacology, and medical uses of amphetamines and other stimulant drugs.
  5. “Drugs and Society” by Glen R. Hanson and Peter J. Venturelli – This book provides a comprehensive overview of the impact of drugs on society and covers a wide range of drugs, including cocaine and amphetamines.

It’s worth noting that, books are a great way to gain knowledge but the information might be outdated, always check the publication date before using it as a reference.