You are currently viewing Difference Between Benzyl Chloride and Benzoyl Chloride

Difference Between Benzyl Chloride and Benzoyl Chloride

  • Post last modified:March 18, 2023
  • Reading time:7 mins read
  • Post category:Biology
  • Post author:

Explanation of Benzyl Chloride and Benzoyl Chloride

Benzyl Chloride and Benzoyl Chloride are two distinct organic compounds with different chemical properties and use.

Benzyl chloride, also known as α-chlorotoluene, is a colorless or pale yellow liquid with a pungent odor. Its chemical formula is C7H7Cl, and it has a molecular weight of 126.59 g/mol. Benzyl chloride is primarily used as a reagent in organic synthesis, particularly in the production of benzyl alcohol.

It is also used as a solvent for cellulose esters and ethers, and as a preservative in the food industry. Benzyl chloride is prepared by the reaction of toluene with chlorine gas or hydrogen chloride gas, or by the reaction of benzyl alcohol with thionyl chloride.

Benzoyl chloride, on the other hand, is a colorless yellowish liquid with a strong odor. Its chemical formula is C7H5ClO, and it has a molecular weight of 140.57 g/mol. Benzoyl chloride is primarily used as a reagent in organic synthesis, particularly in the production of benzoyl peroxide.

It is also used as a reagent for the detection of amino acids in biological samples. Benzoyl chloride is prepared by the reaction of benzo trichloride with aluminum chloride or by the reaction of benzoyl peroxide with hydrogen chloride.

While benzyl chloride and benzoyl chloride share some similarities, such as being used as reagents in organic synthesis, they have distinct differences in their chemical structure, reactivity, and uses. It is important to understand these differences to ensure proper use and safety when handling these compounds.

Importance of understanding the differences between benzyl chloride and benzoyl chloride

Understanding the differences between benzyl chloride and benzoyl chloride is crucial for several reasons:

  1. Chemical synthesis: Benzyl chloride and benzoyl chloride are used as reagents in organic synthesis. Knowing the differences in their reactivity and properties is important for selecting the appropriate reagent and ensuring the success of the reaction.
  2. Industrial applications: Both benzyl chloride and benzoyl chloride have several industrial applications, such as in the production of various chemicals and pharmaceuticals. Understanding the differences between these compounds is essential to ensure their safe and effective use in these applications.
  3. Safety considerations: Both benzyl chloride and benzoyl chloride can pose significant safety hazards if not handled properly. Knowing the differences in their properties and potential hazards can help minimize the risk of accidents and ensure safe handling and storage.

Understanding the differences between benzyl chloride and benzoyl chloride is important for their proper use in various applications, including chemical synthesis and industrial processes, and for ensuring the safety of those handling these compounds.

Benzyl Chloride

Benzyl chloride is an organic compound with the chemical formula C7H7Cl. It is a colorless or pale yellow liquid with a pungent odor. Benzyl chloride is primarily used as a reagent in organic synthesis, particularly in the production of benzyl alcohol. It is also used as a solvent for cellulose esters and ethers, and as a preservative in the food industry.

Benzyl chloride is prepared by the reaction of toluene with chlorine gas or hydrogen chloride gas, or by the reaction of benzyl alcohol with thionyl chloride. It has a molecular weight of 126.59 g/mol and its boiling point is 179 °C.

Benzyl chloride is a reactive compound and can undergo various chemical reactions, including nucleophilic substitution and addition reactions. It is also a hazardous substance that can cause severe skin and eye irritation and damage the respiratory system if inhaled.

Proper safety precautions, such as the use of protective equipment and proper ventilation, should be taken when handling benzyl chloride.

Benzoyl Chloride

Benzoyl chloride is an organic compound with the chemical formula C7H5ClO. It is a colorless to yellowish liquid with a strong odor. Benzoyl chloride is primarily used as a reagent in organic synthesis, particularly in the production of benzoyl peroxide. It is also used as a reagent for the detection of amino acids in biological samples.

Benzoyl chloride is prepared by the reaction of benzo trichloride with aluminum chloride or by the reaction of benzoyl peroxide with hydrogen chloride. It has a molecular weight of 140.57 g/mol and its boiling point is 197 °C.

Like benzyl chloride, benzoyl chloride is a reactive compound that can undergo various chemical reactions, including nucleophilic substitution and addition reactions. It is also a hazardous substance that can cause severe skin and eye irritation and damage the respiratory system if inhaled.

Proper safety precautions, such as the use of protective equipment and proper ventilation, should be taken when handling benzoyl chloride.

Differences between Benzyl Chloride and Benzoyl Chloride

Benzyl chloride and benzoyl chloride are two distinct organic compounds that differ in several ways:

  1. Chemical structure: Benzyl chloride has a benzene ring attached to a methyl group and a chlorine atom, while benzoyl chloride has a benzene ring attached to a carbonyl group and a chlorine atom.
  2. Properties: Benzyl chloride is a colorless or pale yellow liquid with a pungent odor, while benzoyl chloride is a colorless to yellowish liquid with a strong odor. Additionally, benzyl chloride has a lower molecular weight (126.59 g/mol) than benzoyl chloride (140.57 g/mol).
  3. Reactivity: Benzyl chloride is a more reactive compound than benzoyl chloride due to the presence of a methyl group that enhances the reactivity of the benzene ring. Benzyl chloride can undergo nucleophilic substitution and addition reactions, while benzoyl chloride can undergo nucleophilic substitution reactions.
  4. Uses: Benzyl chloride is primarily used as a reagent in organic synthesis for the production of benzyl alcohol and as a solvent for cellulose esters and ethers. Benzoyl chloride is primarily used as a reagent in organic synthesis for the production of benzoyl peroxide and for the detection of amino acids in biological samples.
  5. Hazards: Both benzyl chloride and benzoyl chloride are hazardous substances that can cause skin and eye irritation and damage the respiratory system if inhaled. However, benzyl chloride is more toxic than benzoyl chloride, and its use requires greater safety precautions.

Benzyl chloride and benzoyl chloride differ in their chemical structure, properties, reactivity, uses, and hazards. Understanding these differences is important for their proper use in various applications and for ensuring the safety of those handling these compounds.

Conclusion

Benzyl chloride and benzoyl chloride are two distinct organic compounds that have important applications in various fields, including organic synthesis, industrial processes, and the food industry.

While they share some similarities, such as their hazardous nature and potential to cause skin and eye irritation, they differ in their chemical structure, properties, reactivity, uses, and hazards.

Understanding these differences is crucial for selecting the appropriate reagent in organic synthesis, ensuring the safe handling and storage of these compounds, and minimizing the risk of accidents.

Reference Website

Here are some websites that you can use as references for more information on benzyl chloride and benzoyl chloride:

  1. PubChem: Benzyl Chloride – https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-chloride
  2. PubChem: Benzoyl Chloride – https://pubchem.ncbi.nlm.nih.gov/compound/Benzoyl-chloride
  3. ChemicalBook: Benzyl Chloride – https://www.chemicalbook.com/ChemicalProductProperty_EN_CB8254102.htm
  4. ChemicalBook: Benzoyl Chloride – https://www.chemicalbook.com/ChemicalProductProperty_EN_CB7351905.htm
  5. Sigma-Aldrich: Benzyl Chloride – https://www.sigmaaldrich.com/catalog/product/aldrich/194133
  6. Sigma-Aldrich: Benzoyl Chloride – https://www.sigmaaldrich.com/catalog/product/aldrich/138630